SCHEMBL5607119

SCHEMBL5607119

O=C(Cl)c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.72
KMT2A Q03164 4/20 0.72
ALDH1A1 P00352 3/20 0.72
GLA P06280 3/20 0.72
GAA P10253 3/20 0.72
HPGD P15428 3/20 0.72
MEN1 O00255 3/20 0.69
MAPT P10636 3/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2C19 P33261 1/20 0.64
GFER P55789 1/20 0.64
RAF1 P04049 5/20 0.62
MAPK13 O15264 7/20 0.61
MAPK12 P53778 7/20 0.61
MAPK11 Q15759 7/20 0.61
MAPK14 Q16539 7/20 0.61
GCGR P47871 3/20 0.61
MAPK9 P45984 1/20 0.59
BRAF P15056 2/20 0.58
TP53 P04637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19816007 0.99 KDM4E (0.71) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL2593317 0.88 KDM4E (0.91) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL5074753 0.84 MAPK13 (0.83) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL5943951 0.83 ALOX5 (0.70) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL29103864 0.83 KDM4E (0.83) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL16667652 0.82 MAPK13 (0.83) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL104130 0.82 MAPK13 (0.82) KDM4EKMT2AALDH1A1GLAGAA
Benzene SCHEMBL28852698 0.82 MAPK13 (0.82) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL4552086 0.82 RAF1 (0.88) KDM4EKMT2AALDH1A1GLAGAA
SCHEMBL572542 0.82 KDM4E (0.67) KDM4EKMT2AALDH1A1GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1742661-A2 LIPID COMPOSITIONS AND USE THEREOF Neopharm, Inc. (US) 2007-01-17 EP disclosed
WO-2005067632-A2 LIPID COMPOSITIONS AND USE THEREOF NEOPHARM, INC. (US) 2005-07-28 WO disclosed