SCHEMBL5607121

SCHEMBL5607121

O=C(O)c1c(C(=O)O)c(-c2ccccc2)c(-c2ccccc2)c(C(=O)O)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
FABP3 P05413 2/20 0.44
FABP4 P15090 2/20 0.44
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 3/20 0.42
PTPN1 P18031 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
PTGS2 P35354 1/20 0.42
CDC25B P30305 1/20 0.42
ATM Q13315 1/20 0.42
HNF4A P41235 1/20 0.42
DAO P14920 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446771 0.95 LMNA (0.52) LMNAMAPTHTTFABP3FABP4
SCHEMBL2846662 0.95 LMNA (0.52) LMNAMAPTHTTFABP3FABP4
SCHEMBL11363772 0.92 LMNA (0.50) LMNAMAPTHTTFABP3FABP4
SCHEMBL1635941 0.92 LMNA (0.50) LMNAMAPTHTTFABP3FABP4
SCHEMBL351262 0.90 LMNA (0.48) LMNAMAPTHTTFABP3FABP4
SCHEMBL10405305 0.90 LMNA (0.48) LMNAMAPTHTTFABP3FABP4
SCHEMBL29094128 0.88 CDC25B (0.50) LMNAMAPTHTTALDH1A1HPGD
SCHEMBL352143 0.84 KMO (0.50) LMNAMAPTHTTFABP3FABP4
SCHEMBL29433161 0.84 HNF4A (0.47) LMNAMAPTHTTFABP3FABP4
SCHEMBL17544565 0.84 LMNA (0.44) LMNAMAPTHTTFABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070265381-A1 Thermoplastic Resin Composition and Optical Element Utilizing the Same KONICA MINOLTA OPTO, INC. (JP) 2007-11-15 US disclosed
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed
US-5710238-A Process for preparing branched polycarbonates by solid state polymerization GENERAL ELECTRIC COMPANY (US) 1998-01-20 US disclosed
EP-0801089-A1 Preparation of branched polycarbonates THE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1997-10-15 EP disclosed