Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5607849 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5607568 | 0.77 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL17836078 | 0.72 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL1539598 | 0.71 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL4384850 | 0.71 | DRD2 (0.38) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4089940 | 0.69 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL1681583 | 0.69 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4068961 | 0.69 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7937385 | 0.69 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL1539731 | 0.69 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202316-B2 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-10 | — | — | US | disclosed |
| US-20050192178-A1 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-01 | — | — | US | disclosed |