Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732814 | 0.84 | PIK3CD (0.42) | PIK3CDPIK3CGPIK3CBPIK3R1PIK3CA | |
| SCHEMBL735272 | 0.84 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3CBPIK3R1PIK3CA | |
| SCHEMBL734097 | 0.81 | PIK3CG (0.51) | PIK3CDPIK3CGPIK3CBPIK3R1PIK3CA | |
| SCHEMBL732766 | 0.80 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CBPIK3R1PIK3CA | |
| SCHEMBL735268 | 0.78 | L3MBTL1 (0.47) | PIK3CD | |
| SCHEMBL5607192 | 0.75 | PIK3CG (0.51) | PIK3CDPIK3CGPIK3CBABL1RAD52 | |
| SCHEMBL735150 | 0.73 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CBPIK3R1PIK3CA | |
| SCHEMBL735283 | 0.73 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3CBPIK3R1PIK3CA | |
| SCHEMBL734721 | 0.73 | SMN1; SMN2 (0.51) | PIK3CD | |
| SCHEMBL735101 | 0.73 | LMNA (0.46) | PIK3CDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750715-A1 | METHODS FOR TREATING MAST CELL DISORDERS | ICOS CORPORATION (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005120511-A1 | METHODS FOR TREATING MAST CELL DISORDERS | ICOS CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |