Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455223 | 0.89 | NPC1 (0.36) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL5477563 | 0.88 | RXRB (0.31) | PTAFRKIF11 | |
| SCHEMBL15827904 | 0.86 | ADORA3 (0.32) | NPC1RAB9APTAFR | |
| SCHEMBL3402757 | 0.86 | NR1H4 (0.31) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL1825035 | 0.85 | PDCD1 (0.33) | NPC1RAB9ASMN1; SMN2BRD4 | |
| SCHEMBL22411215 | 0.84 | NPC1 (0.33) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL1799580 | 0.84 | NPC1 (0.33) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL30541994 | 0.84 | NPC1 (0.33) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL3400017 | 0.84 | PTAFR (0.33) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL5548512 | 0.83 | BRD4 (0.32) | NPC1RAB9ALMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131935-B1 | NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2020-06-03 | — | — | EP | disclosed |
| US-10301411-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2019-05-28 | — | — | US | disclosed |
| EP-2746301-B1 | Catalyst | BOREALIS AG (AT) | 2018-05-30 | — | — | EP | disclosed |
| US-9598517-B2 | Catalysts | BOREALIS AG (AT) | 2017-03-21 | — | — | US | disclosed |
| US-9598517-B2 | Catalysts | BOREALIS AG (AT) | 2017-03-21 | — | — | US | disclosed |
| US-20170037164-A1 | NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2017-02-09 | — | — | US | disclosed |
| US-20170037164-A1 | NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2017-02-09 | — | — | US | disclosed |
| US-20150344596-A1 | CATALYSTS | BOREALIS AG (AT) | 2015-12-03 | — | — | US | disclosed |
| US-20150344596-A1 | CATALYSTS | BOREALIS AG (AT) | 2015-12-03 | — | — | US | disclosed |
| US-20150344596-A1 | CATALYSTS | BOREALIS AG (AT) | 2015-12-03 | — | — | US | disclosed |
| EP-1548037-A2 | Random propylene-ethylene copolymers | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| US-6872843-B2 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| EP-1511755-A1 | TRANSITION METAL COMPOUNDS THEIR PREPARATION AND THEIR USE IN CATALYST SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2005-03-09 | — | — | EP | disclosed |
| US-20040171855-A1 | Metallocenes, use in catalyst system for producing olefin polymers | EQUISTAR CHEMICALS, LP | 2004-09-02 | — | — | US | disclosed |
| EP-1397371-A1 | METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Polyolefine GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | EQUISTAR CHEMICALS, LP | 2004-02-05 | — | — | US | disclosed |
| WO-2003106470-A1 | TRANSITION METAL COMPOUNDS THEIR PREPARATION AND THEIR USE IN CATALYST SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2003-12-24 | — | — | WO | disclosed |
| US-6627764-B1 | Titanium, hafnium or zirconium indenyl halide complexes; coordination catalysts | BASELL POLYOLEFINE GMBH (DE) | 2003-09-30 | — | — | US | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| WO-2003000706-A1 | METALLOCENES, USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301411-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | RPS8, MLX, HRH2 | NPC1 2756/4885RAB9A 1006/4885LMNA 804/4885 |
| US-20040171855-A1 | Metallocenes, use in catalyst system for producing olefin polymers | H1-4, H1-0, H1-10 | NPC1 3067/4885RAB9A 2176/4885LMNA 4308/4885 |
| US-20170037164-A1 | NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | RPS8, HRH2, MLX | NPC1 2613/4885RAB9A 753/4885LMNA 646/4885 |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | NPC1 4292/4885RAB9A 4819/4885LMNA 4444/4885 |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | SOAT2, NOTUM, SOAT1 | NPC1 923/4885RAB9A 4353/4885LMNA 4296/4885 |
| US-20150344596-A1 | CATALYSTS | SFN, AP3S1, H1-2 | NPC1 2306/4885RAB9A 1905/4885LMNA 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.