Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 5/20 | 0.70 |
| ▸ | ADORA2A known ✓ | P29274 | 2/20 | 0.70 |
| ▸ | ADORA1 known ✓ | P30542 | 2/20 | 0.70 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.70 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.70 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.70 |
| ▸ | GAPDH | P04406 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | STAT6 | P42226 | 1/20 | 0.70 |
| ▸ | PI4KA | P42356 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.70 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.70 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.70 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.70 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL28391361 | 1.00 | ADORA3 (0.70) | ADORA3ADORA2AADORA1DPP4MEN1 | |
| Adenosine SCHEMBL5981999 | 0.97 | ADORA1 (0.65) | ADORA3ADORA2AADORA1DPP4MEN1 | |
| Adenosine SCHEMBL11028276 | 0.92 | ADORA3 (0.68) | ADORA3ADORA2AADORA1DPP4MEN1 | |
| Adenosine SCHEMBL6803120 | 0.90 | ADORA1 (0.65) | ADORA3ADORA2AADORA1DPP4MEN1 | |
| Niacinamide SCHEMBL28249016 | 0.88 | ADH1A (0.66) | SMN1; SMN2ADH1ANADKIMPDH2IMPDH1 | |
| Adenosine Phosphate SCHEMBL160972 | 0.88 | P2RY1 (0.75) | ADORA1SMN1; SMN2ADH1ANADKIMPDH2 | |
| Adenosine Phosphate SCHEMBL27419541 | 0.88 | P2RY1 (0.75) | ADORA1SMN1; SMN2ADH1ANADKIMPDH2 | |
| Adenosine SCHEMBL9426528 | 0.87 | ADORA3 (0.89) | ADORA3ADORA2AADORA1DPP4MEN1 | |
| Adenosine SCHEMBL2722472 | 0.86 | ADORA3 (0.87) | ADORA3ADORA2AADORA1DPP4MEN1 | |
| Adenosine SCHEMBL27849525 | 0.86 | ADORA3 (0.91) | ADORA3ADORA2AADORA1DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12025557-B2 | Systems, devices, and methods for time-resolved fluorescent spectroscopy | Black Light Surgical, Inc. (US) | 2024-07-02 | — | — | US | claimed |
| US-20230183768-A1 | ENZYMATIC PRODUCTION OF ALLULOSE | Bonumose Inc. | 2023-06-15 | — | — | US | claimed |
| EP-4153767-A2 | ENZYMATIC PRODUCTION OF ALLULOSE | Bonumose Inc. (US) | 2023-03-29 | — | — | EP | claimed |
| CN-115768903-A | Enzymatic production of psicose | 博努莫斯股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| US-20220127653-A1 | ENZYMATIC PRODUCTION OF MANNOSE | X-CALIBER RURAL CAPITAL, LLC | 2022-04-28 | — | — | US | claimed |
| US-11236320-B2 | Enzymatic production of hexoses | BONUMOSE, INC. (US) | 2022-02-01 | — | — | US | claimed |
| EP-3924473-A1 | ENZYMATIC PRODUCTION OF MANNOSE | Bonumose Inc. (US) | 2021-12-22 | — | — | EP | claimed |
| US-20210388404-A1 | ENZYMATIC PRODUCTION OF TAGATOSE | BONUMOSE, INC. | 2021-12-16 | — | — | US | claimed |
| WO-2021236632-A2 | ENZYMATIC PRODUCTION OF ALLULOSE | BONUMOSE, INC. (US) | 2021-11-25 | — | — | WO | claimed |
| CN-113544264-A | Enzymatic production of mannose | 博努莫斯股份有限公司 | 2021-10-22 | — | — | CN | claimed |
| WO-2020081959-A1 | ENZYMATIC PRODUCTION OF TAGATOSE | BONUMOSE LLC (US) | 2020-04-23 | — | — | WO | claimed |
| US-10138506-B2 | Enzymatic production of D-tagatose | BONUMOSE LLC (US) | 2018-11-27 | — | — | US | claimed |
| EP-0680945-A2 | Amino acid, carnitine and magnesium supplementation | OMEARA (PROPRIETARY) LIMITED (SA) | 1995-11-08 | — | — | EP | claimed |
| EP-0484199-B1 | Cosmetic use of an anti-erythema composition | OREAL (FR) | 1994-12-21 | — | — | EP | claimed |
| US-5250290-A | Using nicotinamide adenosine dinucleotide and its phosphate ester encapsulated in lipid vesicles | L'OREAL (FR) | 1993-10-05 | — | — | US | claimed |
| EP-0438386-A4 | NOVEL IMPROVERS FOR FLOUR AND YEAST RAISED BAKED GOODS | — | 1991-09-11 | — | — | EP | claimed |
| EP-0438386-A1 | NOVEL IMPROVERS FOR FLOUR AND YEAST RAISED BAKED GOODS | GEORGE WESTON FOODS LIMITED (AU) | 1991-07-31 | — | — | EP | claimed |
| WO-1988003365-A1 | NOVEL IMPROVERS FOR FLOUR AND YEAST RAISED BAKED GOODS | GEORGE WESTON FOODS LIMITED (AU) | 1988-05-19 | — | — | WO | claimed |
| US-4271264-A | Stabilized liquid enzyme and coenzyme compositions | MEDICAL ANALYSIS SYSTEMS, INC. | 1981-06-02 | — | — | US | claimed |
| US-3934369-A | Vitro net bioxynthesis of chlorophyll and grana | UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1976-01-27 | — | — | US | claimed |