SCHEMBL1398313

SCHEMBL1398313

C=Cc1ccc(C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 3/20 0.32
TP53 P04637 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 1/20 0.31
POLB P06746 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31494218 0.91 ALDH1A1 (0.37) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL31494226 0.91 ALDH1A1 (0.37) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL5080699 0.91 ALDH1A1 (0.33) ALDH1A1
SCHEMBL31494220 0.89 ALDH1A1 (0.34) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL31494230 0.89 ALDH1A1 (0.34) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL31364537 0.82 ALDH1A1 (0.38) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL1405992 0.81 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL5607569 0.80 ALDH1A1 (0.38) ALDH1A1TSHRPOLB
SCHEMBL5606513 0.80 TP53 (0.42) ALDH1A1TSHRTP53MEN1KMT2A
SCHEMBL8760301 0.78 ESR1 (0.52) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638918-A Colored silicon polymer material and preparation method thereof 江苏天眼医药科技股份有限公司 2025-03-18 CN claimed
CN-119569962-A Silicon polymer material and preparation method thereof 烟台爱博诺德医用材料有限公司 2025-03-07 CN claimed
EP-1945231-B1 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL PARTNERS LLP (US) 2021-11-10 EP claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
US-8986725-B2 Silicone-peroxide compositions for long-term, controlled oxygen release UNIVERSITY OF MIAMI (US) 2015-03-24 US claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
US-8784793-B2 Conformable solvent-based bandage and coating material ROCHAL INDUSTRIES, LLP (US) 2014-07-22 US claimed
US-20130303654-A1 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES LLP (US) 2013-11-14 US claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
US-8197803-B2 Method of forming a conformable solvent-based bandage and coating material ROCHAL INDUSTRIES, LLP (US) 2012-06-12 US claimed
US-20120114729-A1 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2012-05-10 US claimed
US-20090210002-A1 METHOD OF FORMING A CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES LLP (US) 2009-08-20 US claimed
US-20070041935-A1 Polymerizable cyanoacrylate monomer and volatile liquid selected from linear and cyclic siloxanes, polydimethylsiloxanes, isooctane, and octane; kits ROCHAL PARTNERS LLP 2007-02-22 US claimed
CN-119638918-A Colored silicon polymer material and preparation method thereof 江苏天眼医药科技股份有限公司 2025-03-18 CN disclosed
CN-119569962-A Silicon polymer material and preparation method thereof 烟台爱博诺德医用材料有限公司 2025-03-07 CN disclosed
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
US-20050131191-A1 High refractive index polymeric siloxysilane compositions SALAMONE JOSEPH C (US) 2005-06-16 US disclosed
US-20030109661-A1 High refractive index polymeric siloxysilane compositions BAUSCH HEALTH US, LLC 2003-06-12 US disclosed
US-20030100697-A1 High refractive index polymeric siloxysilane compositions SALIX PHARMACEUTICALS, INC. 2003-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same CUTA, MMP8, MMP1 ALDH1A1 4110/4885CHRNB2 4458/4885CHRNB4 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.