Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608342 | 0.86 | CRHBP (0.36) | CRHBPCRHR2NPC1RAB9A | |
| SCHEMBL5608407 | 0.83 | — | — | |
| SCHEMBL7734549 | 0.82 | HSD11B1 (0.31) | CRHBPCRHR2 | |
| SCHEMBL5608359 | 0.77 | CRHBP (0.46) | CRHBPCRHR2 | |
| SCHEMBL5608934 | 0.75 | GRIN1 (0.39) | CRHBPCRHR2 | |
| SCHEMBL6232248 | 0.75 | GRIN1 (0.39) | CRHBPCRHR2PKM | |
| SCHEMBL5608156 | 0.75 | CRHBP (0.45) | CRHBPCRHR2 | |
| SCHEMBL6232956 | 0.73 | EPHX1 (0.36) | CRHBPCRHR2 | |
| SCHEMBL5608319 | 0.72 | CRHBP (0.41) | CRHBPCRHR2 | |
| SCHEMBL6227130 | 0.71 | EPHX2 (0.32) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |