Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608156 | 0.97 | CRHBP (0.45) | CRHBPCRHR2 | |
| SCHEMBL5608319 | 0.94 | CRHBP (0.41) | CRHBPCRHR2CA5ACA5B | |
| SCHEMBL5608321 | 0.87 | CRHBP (0.47) | CRHBPCRHR2 | |
| SCHEMBL5917100 | 0.85 | CRHBP (0.50) | CRHBPCRHR2CA5ACA5B | |
| SCHEMBL1075031 | 0.82 | CRHBP (0.42) | CRHBPCRHR2 | |
| SCHEMBL5608068 | 0.82 | CRHBP (0.42) | CRHBPCRHR2 | |
| SCHEMBL5607875 | 0.77 | CRHBP (0.38) | CRHBPCRHR2 | |
| SCHEMBL12858211 | 0.74 | — | — | |
| SCHEMBL6058409 | 0.72 | CRHBP (0.41) | CRHBPCRHR2 | |
| SCHEMBL5191921 | 0.71 | PKM (0.48) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | claimed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | claimed |
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |