Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608178 | 0.82 | PDE4B (0.35) | TRPV1 | |
| SCHEMBL1997127 | 0.75 | GAA (0.39) | TRPV1 | |
| SCHEMBL1995589 | 0.74 | MAPK1 (0.41) | — | |
| SCHEMBL5608071 | 0.74 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL1995355 | 0.73 | PDE4B (0.41) | TRPV1 | |
| SCHEMBL1997021 | 0.73 | MAPK1 (0.41) | — | |
| SCHEMBL1997221 | 0.72 | PDE4B (0.42) | — | |
| SCHEMBL1997288 | 0.71 | PDE4B (0.46) | — | |
| SCHEMBL5607919 | 0.71 | BRAF (0.37) | — | |
| SCHEMBL2001626 | 0.71 | TRPV1 (0.39) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758869-A1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS | Almirall Prodesfarma, S.A. (ES) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123692-A1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS | LABORATORIOS ALMIRALL, S.A. (ES) | 2005-12-29 | — | — | WO | disclosed |