Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17304275 | 1.00 | TSHR (0.36) | TSHRGPR119 | |
| SCHEMBL5307808 | 0.95 | GPR119 (0.34) | TSHRGPR119 | |
| SCHEMBL31032139 | 0.90 | TSHR (0.33) | TSHR | |
| SCHEMBL8181997 | 0.86 | OPRK1 (0.33) | — | |
| SCHEMBL26444547 | 0.78 | — | — | |
| SCHEMBL126707 | 0.78 | — | — | |
| SCHEMBL126686 | 0.78 | — | — | |
| SCHEMBL127016 | 0.78 | — | — | |
| SCHEMBL6550937 | 0.76 | — | — | |
| SCHEMBL320777 | 0.75 | KCNH2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106910-A1 | DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR | FLARE THERAPEUTICS INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-4355748-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2024-04-24 | — | — | EP | disclosed |
| EP-4352055-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2023165570-A1 | CYCLOALKYL OR HETEROCYCLYL SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2023-09-07 | — | — | WO | disclosed |
| WO-2022263472-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022259204-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| EP-3807251-A1 | PHENYL AND PYRIDINYL SUBSTITUTED IMIDAZOLES AS MODULATORS OF RORYT | Janssen Pharmaceutica NV (BE) | 2021-04-21 | — | — | EP | disclosed |
| EP-3652179-A1 | INHIBITORS OF LEUCINE RICH REPEAT KINASE 2 | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2020-05-20 | — | — | EP | disclosed |
| EP-3642195-A1 | SUBSTITUTED 5-CYANOINDOLE COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2020-04-29 | — | — | EP | disclosed |
| WO-2019244000-A1 | PHENYL AND PYRIDINYL SUBSTITUTED IMIDAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
| EP-1487778-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANOLS | Grünenthal GmbH (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080557-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANOLS | Grünenthal GmbH (DE) | 2003-10-02 | — | — | WO | disclosed |
| WO-2001072751-A1 | PYRROLOPYRIMIDINES AS TYROSINE KINASE INHIBITORS | KNOLL GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2001-10-04 | — | — | WO | disclosed |
| EP-0983225-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | Rolic AG (CH) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052905-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 1998-11-26 | — | — | WO | disclosed |
| EP-0207773-B1 | 7-[(Substituted)amino]-8-[(substituted)carbonyl)-methylamino]-1-oxaspiro[4.5]decanes as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4737493-A | 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0207773-A2 | 7-[(Substituted)amino]-8-[(substituted)carbonyl)-methylamino]-1-oxaspiro[4.5]decanes as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4508911-A | Amine intermediates for analgesic compounds | THE UPJOHN COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4438130-A | Analgesic 1-oxa-, aza- and thia-spirocyclic compounds | THE UPJOHN COMPANY (US) | 1984-03-20 | — | — | US | disclosed |