Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612333 | 0.91 | TSHR (0.44) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL2350191 | 0.91 | TSHR (0.44) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL10593447 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRESR1RAB9A | |
| SCHEMBL4247813 | 0.87 | TSHR (0.38) | ALDH1A1LMNATSHRESR1RAB9A | |
| SCHEMBL28515052 | 0.87 | TSHR (0.38) | ALDH1A1LMNATSHRESR1RAB9A | |
| SCHEMBL7568323 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNATSHRRAB9ASMN1; SMN2 | |
| SCHEMBL4331067 | 0.86 | TSHR (0.40) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL4852053 | 0.86 | TSHR (0.40) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL513140 | 0.86 | CYP19A1 (0.39) | ALDH1A1TSHRSLC6A2CYP19A1HPGD | |
| SCHEMBL4851503 | 0.83 | TSHR (0.38) | ALDH1A1LMNATSHRTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791888-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | Promerus, LLC (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023511-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2006-03-02 | — | — | WO | disclosed |