Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134087 | 0.86 | MTNR1A (0.60) | MTNR1AMTNR1BCSF1RCA4 | |
| SCHEMBL9479727 | 0.83 | CA4 (0.56) | CSF1RCA4EGFRPDGFRBKDR | |
| SCHEMBL5277509 | 0.83 | CA4 (0.56) | CSF1RCA4EGFRPDGFRBKDR | |
| SCHEMBL12964972 | 0.81 | TSHR (0.49) | MTNR1AMTNR1BCA4ALDH1A1TSHR | |
| SCHEMBL23618146 | 0.81 | ABL1 (0.53) | MTNR1AMTNR1BCSF1RCYP1A1CYP1A2 | |
| SCHEMBL12047760 | 0.80 | MTNR1A (0.58) | MTNR1AMTNR1BCSF1RCA4 | |
| SCHEMBL12258324 | 0.79 | CHKA (0.47) | ALDH1A1MEN1KMT2AMAPK1EGFR | |
| SCHEMBL30054343 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BALDH1A1CYP3A4 | |
| SCHEMBL1134082 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BALDH1A1CYP3A4 | |
| SCHEMBL13241204 | 0.78 | EGFR (0.50) | CSF1RCA4ALDH1A1EGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210205800-A1 | YLIDE-FUNCTIONALISED PHOSPHANES FOR USE IN METAL COMPLEXES AND HOMOGENEOUS CATALYSIS | UMICORE AG & CO. KG (DE) | 2021-07-08 | — | — | US | disclosed |
| US-10940470-B2 | Ylide-functionalised phosphanes for use in metal complexes and homogeneous catalysis | UMICORE AG & CO. KG (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20200164354-A1 | YLIDE-FUNCTIONALISED PHOSPHANES FOR USE IN METAL COMPLEXES AND HOMOGENEOUS CATALYSIS | UMICORE AG & CO. KG (DE) | 2020-05-28 | — | — | US | disclosed |
| EP-2492274-B1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE AND USE THEREOF | UNIV ZHEJIANG (CN) | 2016-09-21 | — | — | EP | disclosed |
| US-9006491-B2 | Structure and method for synthesizing and using dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate | ZHEJIANG UNIVERSITY (CN) | 2015-04-14 | — | — | US | disclosed |
| EP-2492274-A1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE, PREPARATION METHOD AND USE THEREOF | Zhejiang University (CN) | 2012-08-29 | — | — | EP | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | PTK6, DCLK2, ERBB2 | MTNR1A 4404/4885MTNR1B 2975/4885CSF1R 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.