SCHEMBL5608428

SCHEMBL5608428

CC12CC3CC(O)(C1)CC(C(=O)O)(C3)C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 1/20 0.43
GAA P10253 2/20 0.41
ALOX12 P18054 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 2/20 0.38
ALOX15 P16050 1/20 0.38
P2RX7 Q99572 1/20 0.36
NPC1 O15118 1/20 0.36
HSD11B1 P28845 2/20 0.35
SLC22A1 O15245 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
LMNA P02545 1/20 0.34
ESR1 P03372 1/20 0.34
ADRB3 P13945 1/20 0.34
ACHE P22303 1/20 0.34
OPRK1 P41145 1/20 0.34
MTOR P42345 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003347 0.87 MEN1 (0.58) MEN1KMT2AMAPTGAAALOX12
SCHEMBL5568145 0.87 MEN1 (0.53) MEN1KMT2AMAPTGAAALOX12
SCHEMBL29223865 0.87 MEN1 (0.58) MEN1KMT2AMAPTGAAALOX12
SCHEMBL20604787 0.87 MEN1 (0.58) MEN1KMT2AMAPTGAAALOX12
SCHEMBL8197101 0.86 MEN1 (0.46) MEN1KMT2AMAPTGAAALOX12
SCHEMBL1732678 0.85 HSD11B1 (0.41) MEN1KMT2AGAASMN1; SMN2HSD11B1
SCHEMBL964124 0.85 HSD11B1 (0.41) MEN1KMT2AGAASMN1; SMN2HSD11B1
Hydrochloric Acid SCHEMBL4883396 0.83 MEN1 (0.54) MEN1KMT2AMAPTGAAALOX12
SCHEMBL4098646 0.82 MEN1 (0.41) MEN1KMT2AMAPTGAAALOX12
SCHEMBL4033960 0.81 MEN1 (0.43) MEN1KMT2AMAPTGAAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990425-B1 NOVEL ALICYCLIC ESTER COMPOUND, AND (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME MITSUBISHI GAS CHEMICAL CO (JP) 2018-05-30 EP disclosed
CN-105143291-B Novel alicyclic ester compound, and (meth)acrylic copolymer and photosensitive resin composition containing same 三菱瓦斯化学株式会社 2017-03-22 CN disclosed
US-9477151-B2 Alicyclic ester compound, and (meth)acrylic copolymer and photosensitive resin composition containing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-10-25 US disclosed
US-20160070168-A1 NOVEL ALICYCLIC ESTER COMPOUND, AND (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-03-10 US disclosed
EP-2990425-A1 NOVEL ALICYCLIC ESTER COMPOUND, AND (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2016-03-02 EP disclosed
CN-105143291-A Novel alicyclic ester compound, and (meth)acrylic copolymer and photosensitive resin composition containing same MITSUBISHI GAS CHEMICAL CO 2015-12-09 CN disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
US-RE39744-E1 Adamantane derivatives and process for producing them DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-24 US disclosed
EP-1602975-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-12-07 EP disclosed
US-6392104-B1 CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-21 US disclosed
EP-0927711-A1 ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM Daicel Chemical Industries, Ltd. (JP) 1999-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS APP, BACE1, IAPP MEN1 2310/4885KMT2A 4781/4885MAPT 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.