Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559746 | 0.87 | HSD11B1 (0.40) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL5351544 | 0.87 | HSD11B1 (0.40) | MEN1KMT2AMAPTSMN1; SMN2HSD11B1 | |
| SCHEMBL7453250 | 0.87 | MEN1 (0.58) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL5608428 | 0.86 | MEN1 (0.46) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL4098646 | 0.82 | MEN1 (0.41) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL4033960 | 0.81 | MEN1 (0.43) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL7733822 | 0.80 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2HSD11B1LMNA | |
| Acetamide SCHEMBL27589963 | 0.79 | GRIN1 (0.47) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL7735482 | 0.79 | PKM (0.44) | MEN1KMT2AMAPTGAAALOX12 | |
| SCHEMBL25472233 | 0.78 | GRIN1 (0.52) | MEN1KMT2AMAPTGAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990634-B1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | DAICEL CHEM (JP) | 2013-04-10 | — | — | EP | disclosed |
| EP-0990634-A1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | Daicel Chemical Industries, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |