Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759000 | 0.78 | EGFR (0.35) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL391322 | 0.78 | EGFR (0.35) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL568314 | 0.78 | EGFR (0.35) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL9985983 | 0.73 | EGFR (0.36) | KDM1ASLC6A4DRD2IDO1ALDH1A1 | |
| SCHEMBL2155195 | 0.73 | KDM1A (0.43) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL14721427 | 0.72 | ACP3 (0.36) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL7775994 | 0.71 | KDM1A (0.38) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL5248281 | 0.71 | KDM1A (0.38) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL10476854 | 0.71 | KDM1A (0.38) | KDM1ASLC6A4DRD2IDO1KDM4E | |
| SCHEMBL11614041 | 0.71 | KDM1A (0.38) | KDM1ASLC6A4DRD2IDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |