Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155195 | 0.83 | KDM1A (0.43) | KDM1ASLC6A4DRD2IDO1MAPT | |
| SCHEMBL5248281 | 0.81 | KDM1A (0.38) | KDM1AHSD11B1SLC6A4DRD2IDO1 | |
| SCHEMBL10476854 | 0.81 | KDM1A (0.38) | KDM1AHSD11B1SLC6A4DRD2IDO1 | |
| SCHEMBL11614041 | 0.81 | KDM1A (0.38) | KDM1AHSD11B1SLC6A4DRD2IDO1 | |
| SCHEMBL20597643 | 0.80 | HSD11B1 (0.37) | KDM1AHSD11B1SLC6A4DRD2IDO1 | |
| SCHEMBL7999943 | 0.78 | KDM1A (0.39) | KDM1ASLC6A4DRD2IDO1MAPT | |
| SCHEMBL4480218 | 0.77 | SLC6A4 (0.36) | KDM1ASLC6A4DRD2IDO1MAPT | |
| SCHEMBL8506986 | 0.77 | SLC6A4 (0.36) | KDM1ASLC6A4DRD2IDO1MAPT | |
| SCHEMBL14931728 | 0.77 | IDO1 (0.36) | KDM1AHSD11B1SLC6A4DRD2IDO1 | |
| SCHEMBL6749603 | 0.77 | SLC6A4 (0.37) | KDM1AHSD11B1SLC6A4DRD2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673944-B1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-16 | — | — | EP | claimed |
| EP-0663378-B1 | Process for preparing of 2,2'-dimethyl-1, 1'-binaphthalene and 2,7'-Dimethyl-1,1'binaphthalene | HOECHST AG (DE) | 1999-03-31 | — | — | EP | claimed |
| US-5750728-A | TREATING AROMATIC METHYL COMPOUND DISSOLVED IN CHLOROBENZENE WITH N-BROMOSUCCINIMIDE | CLARIANT GMBH (DE) | 1998-05-12 | — | — | US | claimed |
| EP-0663378-A1 | 2,7'-Dimethyl-1,1'-bioaphthalene and process for preparing of 2,2'-dimethyl-1,1'-binaphthalene and 2,7'-Dimethyl-1,1'binaphthalene | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-19 | — | — | EP | claimed |
| US-5750728-A | TREATING AROMATIC METHYL COMPOUND DISSOLVED IN CHLOROBENZENE WITH N-BROMOSUCCINIMIDE | CLARIANT GMBH (DE) | 1998-05-12 | — | — | US | disclosed |
| EP-0595150-B1 | Process for the preparation of aromatic bromomethylcompounds | HOECHST AG (DE) | 1996-07-31 | — | — | EP | disclosed |
| EP-0155637-B2 | Separation agent | DAICEL CHEM (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0663378-A1 | 2,7'-Dimethyl-1,1'-bioaphthalene and process for preparing of 2,2'-dimethyl-1,1'-binaphthalene and 2,7'-Dimethyl-1,1'binaphthalene | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-19 | — | — | EP | disclosed |
| EP-0663378-A1 | 2,7'-Dimethyl-1,1'-bioaphthalene and process for preparing of 2,2'-dimethyl-1,1'-binaphthalene and 2,7'-Dimethyl-1,1'binaphthalene | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-19 | — | — | EP | disclosed |
| EP-0595150-A1 | Process for the preparation of aromatic bromomethylcompounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0155637-B1 | SEPARATION AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |
| US-4619970-A | CHROMATOGRAPHIC RESOLUING AGENT OF SILION GEL BONDED TO OPTICALLY ACTIVE POLYMER | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0155637-A2 | Separation agent | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-09-25 | — | — | EP | disclosed |