SCHEMBL5248281

SCHEMBL5248281

OC1(O)C=Cc2ccccc2C1c1cccc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.38
IDO1 P14902 1/20 0.36
KDM4E B2RXH2 1/20 0.35
TDP2 O95551 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP3 P42574 1/20 0.35
HTT P42858 1/20 0.35
GALK1 P51570 1/20 0.35
BLM P54132 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11614041 1.00 KDM1A (0.38) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL7999943 0.84 KDM1A (0.39) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL2155195 0.83 KDM1A (0.43) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL4800303 0.81 KDM4E (0.43) KDM4EALDH1A1MAPTHTTNPSR1
SCHEMBL7775994 0.81 KDM1A (0.38) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL10476854 0.81 KDM1A (0.38) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL8506986 0.80 SLC6A4 (0.36) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL20597643 0.80 HSD11B1 (0.37) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL5619561 0.80 GPR84 (0.36) KDM1AIDO1KDM4ETDP2ALDH1A1
SCHEMBL8828017 0.80 GPR84 (0.36) KDM1AIDO1KDM4ETDP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5266723-A Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids MEDICE, LTD., CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) 1993-11-30 US claimed
JP-5015381-A None JP disclosed
EP-1026545-B1 Heat developable photosensitive material FUJIFILM CORP (JP) 2007-09-26 EP disclosed
EP-0974866-B1 Heat-developable image-recording material FUJI PHOTO FILM CO LTD (JP) 2006-10-18 EP disclosed
EP-0911691-B2 Recording elements and making methods FUJI PHOTO FILM CO LTD (JP) 2005-04-13 EP disclosed
EP-0838722-B1 Photothermographic material containing a 2,3-dihydrothiazole derivative FUJI PHOTO FILM CO LTD (JP) 2005-01-12 EP disclosed
EP-0902322-B1 Thermographic image-recording elements FUJI PHOTO FILM CO LTD (JP) 2003-11-26 EP disclosed
EP-0903629-B1 HEAT DEVELOPING PHOTOSENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO LTD (JP) 2003-07-09 EP disclosed
US-6562561-B1 Dimensional change over time after the heat development can be prevented by using a support which is coated on both sides with undercoat layers comprising a vinylidene chloride copolymer FUJI PHOTO FILM CO., LTD. (JP) 2003-05-13 US disclosed
US-6479221-B1 IMAGE-FORMING LAYER CONTAINING AN ORGANIC SILVER SALT, A REDUCING AGENT, AND A PHOTOSENSITIVE SILVER HALIDE ON A SUPPORT, AND AT LEAST ONE PROTECTING LAYER(S) IS/ARE PLACED ON THE IMAGE-FORMING LAYER FUJI PHOTO FILM CO., LTD. (JP) 2002-11-12 US disclosed
EP-0883022-A1 Coating method for thermographic imaging element, coating solution for thermographic image forming layer, thermographic imaging element, and photothermographic imaging element FUJI PHOTO FILM CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0838722-A2 Photothermographic material, novel 2,3-dihydrothiazole derivative, and photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0829753-A1 Photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-18 EP disclosed
US-5380927-A Process for preparing optically active 2-aryl-alkanoic acids, in particular 2-aryl-propionic acids MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) 1995-01-10 US disclosed
EP-0599463-A2 High speed, dry processed printing plate construction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-01 EP disclosed
US-5266723-A Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids MEDICE, LTD., CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) 1993-11-30 US disclosed
JP-H0515381-A PRODUCTION OF 1,1'-BINAPHTHALENE-2,2'-DIOL MERCIAN CORP 1993-01-26 JP disclosed
EP-0375611-A1 Enantiomeric silanes, modified support and its use CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4043979-A Polymer-multiheteromacrocycles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1977-08-23 US disclosed
JP-H00515381-A 0001-01-01 JP disclosed