SCHEMBL391322

SCHEMBL391322

C1=CC(P(c2ccccc2)c2ccccc2)(P(c2ccccc2)c2ccccc2)C(c2cccc3ccccc23)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 8/20 0.35
ERBB2 P04626 8/20 0.35
KDM1A O60341 1/20 0.34
IDO1 P14902 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TDP2 O95551 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32
HTT P42858 1/20 0.32
GALK1 P51570 1/20 0.32
BLM P54132 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
KDM4C Q9H3R0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759000 1.00 EGFR (0.35) EGFRERBB2KDM1AIDO1KDM4E
SCHEMBL568314 1.00 EGFR (0.35) EGFRERBB2KDM1AIDO1KDM4E
SCHEMBL1680560 0.91 EGFR (0.39) EGFRERBB2KDM1AIDO1KDM4E
SCHEMBL9985983 0.89 EGFR (0.36) EGFRERBB2KDM1AIDO1ALDH1A1
SCHEMBL1578331 0.88
SCHEMBL5700201 0.80 EGFR (0.34) EGFRERBB2KDM1AKDM4ETDP2
SCHEMBL2155195 0.79 KDM1A (0.43) EGFRERBB2KDM1AIDO1KDM4E
SCHEMBL18980719 0.78 KDM4E (0.34) EGFRERBB2KDM1AKDM4ESLC6A4
SCHEMBL5609115 0.78 KDM1A (0.33) KDM1AIDO1KDM4EALDH1A1SLC6A4
SCHEMBL7775994 0.76 KDM1A (0.38) EGFRERBB2KDM1AIDO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220033391-A1 SOLID FORM, CRYSTALLINE FORM, AND CRYSTAL FORM A OF FXR AGONIST, AND PREPARATION METHOD AND APPLICATION THEREOF CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) 2022-02-03 US claimed
EP-2708527-B1 ALDEHYDE COMPOUND PRODUCTION METHOD MITSUI CHEMICALS INC (JP) 2019-03-20 EP claimed
US-20170173572-A1 CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-06-22 US claimed
US-9227925-B2 Process for producing aldehyde compounds MITSUI CHEMICALS, INC. (JP) 2016-01-05 US claimed
US-12637421-B2 Anthraquinone compound, liquid crystal composition containing said compound, and dimming element NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
US-12612410-B2 Multi-cyclic IRAK and FLT3 inhibiting compounds and uses thereof CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2026-04-28 US disclosed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed
US-20260042755-A1 GPR6 INVERSE AGONISTS MAPLIGHT THERAPEUTICS INC (US) 2026-02-12 US disclosed
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS INC (US) 2026-01-29 US disclosed
EP-4658659-A2 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF Children's Hospital Medical Center (US) 2025-12-10 EP disclosed
US-20250368648-A1 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-12-04 US disclosed
US-12465603-B2 Phthalazinone based modulators for the treatment of disease SOLEY THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
EP-0295109-B2 Process for preparing optically active alcohol TAKASAGO PERFUMERY CO LTD (JP) 1996-09-04 EP disclosed
EP-0403188-B1 A compound of 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl and catalytic complexes thereof TAKASAGO PERFUMERY CO LTD (JP) 1994-12-07 EP disclosed
EP-0297752-B1 PROCESS OF PREPARING OPTICALLY ACTIVE ALCOHOL Takasago International Corporation (JP) 1992-09-16 EP disclosed
EP-0403188-A3 A COMPOUND OF 2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL AND CATALYTIC COMPLEXES THEREOF Takasago International Corporation (JP) 1991-08-28 EP disclosed
EP-0403188-A2 A compound of 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl and catalytic complexes thereof Takasago International Corporation (JP) 1990-12-19 EP disclosed
US-4933482-A HYDROGENATION OF BETA-KETO ACID IN PRESENCE OF RUTHENIUM PHOSPHINE COMPLEX TAKASAGO INTERNATIONAL CORPORATION (JP) 1990-06-12 US disclosed
US-4916252-A OPTICALLY ACTIVE PHOSPHINE-RUTHENIUM HYDROGENATION CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 1990-04-10 US disclosed
EP-0297752-A2 Process of preparing optically active alcohol Takasago International Corporation (JP) 1989-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033391-A1 SOLID FORM, CRYSTALLINE FORM, AND CRYSTAL FORM A OF FXR AGONIST, AND PREPARATION METHOD AND APPLICATION THEREOF SLC10A1, FXR1, NR1H4 EGFR 1510/4885ERBB2 3559/4885KDM1A 3934/4885
US-20170173572-A1 CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS POF1B, FGFR1, COASY EGFR 302/4885ERBB2 841/4885KDM1A 1675/4885
US-12465603-B2 Phthalazinone based modulators for the treatment of disease MKI67, BCL2, CCAR2 EGFR 728/4885ERBB2 340/4885KDM1A 1073/4885
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE NCOR1, NOP56, NCOR2 EGFR 182/4885ERBB2 265/4885KDM1A 2756/4885
US-20260042755-A1 GPR6 INVERSE AGONISTS GPR6, GPR3, GPR4 EGFR 378/4885ERBB2 703/4885KDM1A 4043/4885
US-12637421-B2 Anthraquinone compound, liquid crystal composition containing said compound, and dimming element ACIN1, ANTXR2, CXCR1 EGFR 4517/4885ERBB2 3702/4885KDM1A 1159/4885
US-12612410-B2 Multi-cyclic IRAK and FLT3 inhibiting compounds and uses thereof FLT3, IRAK3, IRAK2 EGFR 523/4885ERBB2 111/4885KDM1A 305/4885
US-20250368648-A1 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF FLT3, IRAK1, IRAK2 EGFR 241/4885ERBB2 103/4885KDM1A 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.