SCHEMBL5609669

SCHEMBL5609669

CCCCCCc1ccc(C(=O)O)c(C)c1

nearest known ligand 0.78

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.78
PPARA Q07869 2/20 0.72
KAT8 Q9H7Z6 2/20 0.68
PPARG P37231 1/20 0.67
RARA P10276 2/20 0.61
RARG P13631 1/20 0.61
PLK1 P53350 6/20 0.59
PLK3 Q9H4B4 1/20 0.59
MEN1 O00255 1/20 0.58
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.58
MTOR P42345 1/20 0.58
KMT2A Q03164 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11028587 1.00 RARB (0.78) RARBPPARAKAT8PPARGRARA
SCHEMBL4308582 1.00 RARB (0.78) RARBPPARAKAT8PPARGRARA
SCHEMBL20503376 1.00 RARB (0.78) RARBPPARAKAT8PPARGRARA
SCHEMBL551744 0.93 RARB (0.68) RARBPPARAKAT8PPARGRARA
SCHEMBL4187659 0.88 RARB (1.00) RARBPPARAKAT8PPARGRARA
SCHEMBL4611393 0.88 RARB (1.00) RARBPPARAKAT8PPARGRARA
SCHEMBL3033031 0.87 KAT8 (0.77) RARBPPARAKAT8PPARGRARA
SCHEMBL10792437 0.87 KAT8 (0.77) RARBPPARAKAT8PPARGRARA
SCHEMBL9665751 0.87 KAT8 (0.77) RARBPPARAKAT8PPARGRARA
SCHEMBL3029363 0.87 KAT8 (0.77) RARBPPARAKAT8PPARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377473-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-06-19 EP disclosed
US-20230133817-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2023-05-04 US disclosed
US-20230133817-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2023-05-04 US disclosed
CN-107526256-B Toner compositions with anti-plasticizers 施乐公司 2023-04-07 CN disclosed
CN-108884058-B Macrocyclic broad spectrum antibiotics 阿奇克斯制药公司 2022-04-29 CN disclosed
CN-108884058-A MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS 阿奇克斯制药公司 2018-11-23 CN disclosed
US-20180327367-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS WUXI APPTEC CO., LTD (CN) 2018-11-15 US disclosed
EP-3377473-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX Pharmaceuticals, Inc. (US) 2018-09-26 EP disclosed
EP-2555273-B1 ORGANIC ELECTRIC-FIELD LIGHT-EMITTING DEVICE MATERIAL, ORGANIC ELECTRIC-FIELD LIGHT-EMITTING DEVICE FORMED OF SAME, AND METHOD FOR MANUFACTURING ORGANIC ELECTRIC-FIELD LIGHT-EMITTING DEVICE UDC IRELAND LTD (IE) 2017-09-27 EP disclosed
US-9601705-B2 Material for organic electroluminescence element and organic electroluminescence element using the same, and method for manufacturing organic electroluminescence element UDC IRELAND LIMITED (IE) 2017-03-21 US disclosed
EP-1354887-B1 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INST TECHNOLOGY (US) 2007-04-25 EP disclosed
US-7067230-B2 Photorefractive composite NITTO DENKO CORPORATION (JP) 2006-06-27 US disclosed
EP-1097158-B1 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INST TECHNOLOGY (US) 2006-01-25 EP disclosed
US-20050209478-A1 Polydioxaborines ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2005-09-22 US disclosed
US-6916894-B2 Polydioxaborines NITTO DENKO CORPORATION (JP) 2005-07-12 US disclosed
EP-1490377-A1 POLYDIOXABORINES, THEIR MONOMERS AND THEIR PREPARATION Nitto Denko Corporation (JP) 2004-12-29 EP disclosed
US-20040200999-A1 Photorefractive composite NITTO DENKO CORPORATION (JP) 2004-10-14 US disclosed
US-20030220500-A1 An acrylic ester polymers comprise a 1,3,2- dioxaborine group in the side chain; soluble, film formers, and have semiconducting properties NITTO DENKO CORPORATION (JP) 2003-11-27 US disclosed
EP-1354887-A1 Ligands for metals and improved metal-catalyzed processes based thereon Massachusetts Insitute of Technology (US) 2003-10-22 EP disclosed
WO-2003084968-A1 POLYDIOXABORINES, THEIR MONOMERS AND THEIR PREPARATION NITTO DENKO CORPORATION (JP) 2003-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209478-A1 Polydioxaborines DAXX, PUF60, DCAF7 RARB 1519/4885PPARA 3941/4885KAT8 4607/4885
US-20180327367-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS MRPL21, PEPD, CTSC RARB 1554/4885PPARA 3021/4885KAT8 4090/4885
US-20230133817-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS MRPL21, PEPD, CTSC RARB 1554/4885PPARA 3021/4885KAT8 4090/4885
US-20030220500-A1 An acrylic ester polymers comprise a 1,3,2- dioxaborine group in the side chain; soluble, film formers, and have semiconducting properties DAXX, CAD, PUF60 RARB 1101/4885PPARA 3060/4885KAT8 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.