SCHEMBL560972

SCHEMBL560972

c1ccc(CNc2nncnn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.48
FABP1 P07148 1/20 0.47
FABP6 P51161 1/20 0.47
RAD52 P43351 2/20 0.46
KMT2A Q03164 3/20 0.46
POLB P06746 1/20 0.46
KDM5B Q9UGL1 1/20 0.45
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
APP P05067 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
UBE2N P61088 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RCE1 Q9Y256 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GALR3 O60755 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4590092 0.78 FABP1 (0.52) KCNH3FABP1FABP6KMT2AKDM5B
SCHEMBL28931524 0.77 GAA (0.56) KCNH3KMT2ALMNAGAAMEN1
SCHEMBL3298289 0.77 KCNH3 (0.73) KCNH3RAD52KMT2APOLBLMNA
SCHEMBL23989829 0.75 MAPT (0.53) KMT2APOLBLMNAGAAMEN1
SCHEMBL9779691 0.74 FABP1 (0.52) KCNH3FABP1FABP6KMT2ALMNA
SCHEMBL1413125 0.73 FABP1 (0.67) FABP1FABP6KMT2AMEN1ALDH1A1
Hydrochloric Acid SCHEMBL28584936 0.72 KCNH3 (0.52) KCNH3FABP1FABP6KMT2ALMNA
SCHEMBL28475529 0.71 FABP1 (0.64) FABP1FABP6KMT2AMEN1ALDH1A1
SCHEMBL15900559 0.69 FABP1 (0.61) FABP1FABP6KMT2AKDM5BLMNA
SCHEMBL1924100 0.69 HTT (0.78) KMT2AGAAMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119896633-A Hydrogel cold compress and cold and hot compress set prepared from hydrogel cold compress and application of hydrogel cold compress 中国人民解放军空军军医大学 2025-04-29 CN claimed
US-11786600-B2 Cliptac composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-10-17 US claimed
CN-112126081-B Fast-curable hydrogel based on inverse Diels-Alder reaction, and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-01-31 CN claimed
CN-112126069-B Rapidly curable hydrogel based on collagen and hyaluronic acid, preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2021-12-21 CN claimed
CN-112126081-A Fast-curable hydrogel based on inverse Diels-Alder reaction, and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2020-12-25 CN claimed
CN-112126069-A Rapidly curable hydrogel based on collagen and hyaluronic acid, preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2020-12-25 CN claimed
US-20190275161-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2019-09-12 US claimed
WO-2017212329-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-12-14 WO claimed
CN-102271712-B For by substance delivery to the compositions of biological target and method THE GENERAL HOSPITAL CORP. (US) 2015-11-25 CN claimed
EP-3474901-B1 CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION TAGWORKS PHARMACEUTICALS B V (NL) 2025-08-06 EP disclosed
CN-119896633-A Hydrogel cold compress and cold and hot compress set prepared from hydrogel cold compress and application of hydrogel cold compress 中国人民解放军空军军医大学 2025-04-29 CN disclosed
US-12186405-B2 Cleavable tetrazine used in bio-orthogonal drug activation TAGWORKS PHARMACEUTICALS B.V. (NL) 2025-01-07 US disclosed
US-12161734-B2 Multimodal silica-based nanoparticles SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2024-12-10 US disclosed
US-20240131169-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-04-25 US disclosed
US-20110268654-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION (US) 2011-11-03 US disclosed
WO-2011112970-A2 COMPOSITIONS AND METHODS FOR BIOCONJUGATION TO QUANTUM DOTS THE GENERAL HOSPITAL CORPORATION (US) 2011-09-15 WO disclosed
EP-2361098-A2 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET The General Hospital Corporation (US) 2011-08-31 EP disclosed
WO-2010119389-A2 PRETARGETING KIT, METHOD AND AGENTS USED THEREIN KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-10-21 WO disclosed
WO-2010119382-A1 PRETARGETING KIT, METHOD AND AGENTS USED THEREIN KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-10-21 WO disclosed
WO-2010051530-A2 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION (US) 2010-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110268654-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET FCER2, EPCAM, EPHA2 KCNH3 4694/4885FABP1 199/4885FABP6 1493/4885
US-11786600-B2 Cliptac composition UBE3C, CBLC, STUB1 KCNH3 4810/4885FABP1 1359/4885FABP6 2445/4885
US-20190275161-A1 CLIPTAC COMPOSITION UBE3C, CBLC, STUB1 KCNH3 4810/4885FABP1 1359/4885FABP6 2445/4885
US-20240131169-A1 CLIPTAC COMPOSITION UBE3C, CBLC, STUB1 KCNH3 4810/4885FABP1 1359/4885FABP6 2445/4885
US-12186405-B2 Cleavable tetrazine used in bio-orthogonal drug activation KIT, TPSB2, BTD KCNH3 3247/4885FABP1 3309/4885FABP6 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.