Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159741 | 0.91 | HSD11B1 (0.53) | HSD11B1ALDH1A1PREPPKML3MBTL1 | |
| SCHEMBL17636389 | 0.91 | HSD11B1 (0.53) | HSD11B1ALDH1A1PREPPKML3MBTL1 | |
| SCHEMBL14455208 | 0.91 | HSD11B1 (0.53) | HSD11B1ALDH1A1PREPPKML3MBTL1 | |
| SCHEMBL5346781 | 0.89 | HSD11B1 (0.54) | HSD11B1ALDH1A1PREPPKMCNR2 | |
| SCHEMBL587576 | 0.79 | HSD11B1 (0.49) | HSD11B1ALDH1A1PKML3MBTL1CNR2 | |
| SCHEMBL5609809 | 0.79 | HSD11B1 (0.40) | HSD11B1ALDH1A1PREPPKML3MBTL1 | |
| SCHEMBL4102876 | 0.78 | HSD11B1 (0.47) | HSD11B1ALDH1A1PREPPKML3MBTL1 | |
| SCHEMBL1055413 | 0.78 | HSD11B1 (0.47) | HSD11B1ALDH1A1PREPPKML3MBTL1 | |
| SCHEMBL5356850 | 0.78 | SMN1; SMN2 (0.50) | HSD11B1ALDH1A1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL28845132 | 0.76 | HSD11B1 (0.56) | HSD11B1ALDH1A1PREPPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023052-A | Synthesis process for 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid | ALBEMARLE CORP (US) | 2007-08-22 | — | — | CN | disclosed |
| EP-1789376-A1 | SYNTHESIS PROCESS FOR 2-(3-HYDROXY-1-ADAMANTYL)-2-OXOACETIC ACID | ALBEMARLE CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006034175-A1 | SYNTHESIS PROCESS FOR 2-(3-HYDROXY-1-ADAMANTYL)-2-OXOACETIC ACID | ALBEMARLE CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |