Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346781 | 0.82 | HSD11B1 (0.54) | HSD11B1ALDH1A1CNR2CNR1ABL1 | |
| SCHEMBL5609803 | 0.79 | HSD11B1 (0.46) | HSD11B1ALDH1A1CNR2CNR1ABL1 | |
| SCHEMBL27560710 | 0.79 | DPP4 (0.42) | ALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL2623074 | 0.77 | HSD11B1 (0.47) | HSD11B1ALDH1A1CNR2CNR1ABL1 | |
| SCHEMBL22728354 | 0.77 | PKM (0.39) | HSD11B1ALDH1A1CNR2CNR1ABL1 | |
| SCHEMBL3290103 | 0.75 | DPP8 (0.37) | HSD11B1ALDH1A1CNR2NPSR1PKM | |
| SCHEMBL15281467 | 0.75 | PKM (0.37) | HSD11B1ALDH1A1NPSR1PKMDPP8 | |
| SCHEMBL13015773 | 0.75 | PKM (0.37) | HSD11B1ALDH1A1L3MBTL1NPSR1PKM | |
| SCHEMBL13383446 | 0.75 | PKM (0.37) | HSD11B1ALDH1A1NPSR1PKMDPP8 | |
| SCHEMBL41045 | 0.75 | PKM (0.37) | HSD11B1ALDH1A1NPSR1PKMDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023052-A | Synthesis process for 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid | ALBEMARLE CORP (US) | 2007-08-22 | — | — | CN | disclosed |
| EP-1789376-A1 | SYNTHESIS PROCESS FOR 2-(3-HYDROXY-1-ADAMANTYL)-2-OXOACETIC ACID | ALBEMARLE CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006034175-A1 | SYNTHESIS PROCESS FOR 2-(3-HYDROXY-1-ADAMANTYL)-2-OXOACETIC ACID | ALBEMARLE CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |