Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599399 | 1.00 | ALDH1A1 (0.35) | ALDH1A1DGAT1APOBEC3AAPOBEC3GOPRM1 | |
| SCHEMBL5611023 | 0.92 | TP53 (0.35) | ALDH1A1DGAT1 | |
| SCHEMBL5611015 | 0.92 | TP53 (0.35) | ALDH1A1DGAT1 | |
| SCHEMBL5599047 | 0.84 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYK | |
| SCHEMBL5599054 | 0.84 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYK | |
| SCHEMBL14370497 | 0.83 | ALDH1A1 (0.37) | ALDH1A1DGAT1IDH1 | |
| SCHEMBL5404822 | 0.83 | ALDH1A1 (0.35) | ALDH1A1APOBEC3AAPOBEC3GSYKCFTR | |
| SCHEMBL5404818 | 0.83 | ALDH1A1 (0.35) | ALDH1A1APOBEC3AAPOBEC3GSYKCFTR | |
| SCHEMBL4726527 | 0.80 | ALDH1A1 (0.39) | ALDH1A1APOBEC3AAPOBEC3GOPRM1OPRD1 | |
| SCHEMBL4726531 | 0.80 | ALDH1A1 (0.39) | ALDH1A1APOBEC3AAPOBEC3GOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147794-A1 | FURAN DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |