SCHEMBL5611271

SCHEMBL5611271

CCOC(=O)C(C(=O)OCC)(C(C)Cl)C(C)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.43
ALDH1A1 P00352 4/20 0.40
PKM P14618 3/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP4F2 P78329 2/20 0.37
CYP4A11 Q02928 2/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
ABCB11 O95342 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235893 0.81 MMP8 (0.46) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL27634711 0.80 MMP8 (0.42) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL5611219 0.77 MMP8 (0.43) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL1769789 0.74 ALDH1A1 (0.42) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL11649142 0.74 ALDH1A1 (0.42) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL28776204 0.74 ALDH1A1 (0.41) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL15233830 0.73 KCNN4 (0.37) ALDH1A1
SCHEMBL3829694 0.72 MMP8 (0.47) MMP8ALDH1A1PKMLMNAHSD17B10
SCHEMBL20445644 0.71
SCHEMBL15114063 0.71 MMP8 (0.46) MMP8ALDH1A1PKMLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
US-20140206827-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-07-24 US disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed