SCHEMBL235893

SCHEMBL235893

CCOC(=O)C(C(=O)OCC)(C(C)C)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.46
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PKM P14618 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
CYP4F2 P78329 3/20 0.39
CYP4A11 Q02928 3/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.38
PIN1 Q13526 1/20 0.37
TRPA1 O75762 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28776204 0.87 ALDH1A1 (0.41) MMP8ALDH1A1LMNAHSD17B10PKM
SCHEMBL27836874 0.86 ALDH1A1 (0.45) MMP8ALDH1A1PKMMEN1KMT2A
SCHEMBL16501326 0.83 MMP8 (0.46) MMP8ALDH1A1LMNAHSD17B10PKM
SCHEMBL16797815 0.82 MEN1 (0.44) MMP8ALDH1A1LMNAHSD17B10PKM
SCHEMBL5611219 0.81 MMP8 (0.43) MMP8ALDH1A1LMNAHSD17B10PKM
SCHEMBL5611271 0.81 MMP8 (0.43) MMP8ALDH1A1LMNAHSD17B10PKM
SCHEMBL232410 0.81 HCAR2 (0.38) MMP8ALDH1A1LMNAHSD17B10ATM
SCHEMBL28004681 0.80 EPHX1 (0.40) MMP8ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11879021 0.78 MMP8 (0.44) MMP8ALDH1A1LMNAHSD17B10PKM
SCHEMBL1605028 0.78 MMP8 (0.48) MMP8ALDH1A1LMNAHSD17B10PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661883-B Solid catalyst component for preparing polyolefin, catalyst system and application thereof 中国石油化工股份有限公司 2022-10-21 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
US-10822438-B2 Catalyst system for enhanced stereo-specificity of olefin polymerization and method for producing olefin polymer FORMOSA PLASTICS CORPORATION (US) 2020-11-03 US claimed
EP-3053935-B1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME CHINA PETROLEUM & CHEM CORP (CN) 2019-05-08 EP claimed
CN-106632752-B A kind of olefine polymerizing process 营口风光新材料股份有限公司 2019-04-02 CN claimed
CN-106832069-B A kind of catalyst and preparation method thereof for olefinic polymerization 营口风光新材料股份有限公司 2019-03-08 CN claimed
US-20180327520-A1 Catalyst system for enhanced stereo-specificity of olefin polymerization and method for producing olefin polymer FORMOSA PLASTICS CORPORATION, USA 2018-11-15 US claimed
US-9822196-B2 Catalyst composition for olefin polymerization and application of same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-11-21 US claimed
CN-104513330-B A kind of catalyst systems for olefin polymerization and its application 中国石油化工股份有限公司 2017-07-28 CN claimed
CN-106832069-A A kind of catalyst for olefinic polymerization and preparation method thereof 营口市风光化工有限公司 2017-06-13 CN claimed
CN-106632752-A Olefin polymerization method 营口市风光化工有限公司 2017-05-10 CN claimed
CN-104513327-B Olefin polymerization catalyst composition and applications thereof 中国石油化工股份有限公司 2017-02-15 CN claimed
US-20160244538-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-08-25 US claimed
EP-3053935-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME China Petroleum & Chemical Corporation (CN) 2016-08-10 EP claimed
CN-105315390-A Catalyst composition for olefin polymerization and application thereof BEIJING COMBINE TECH CO LTD 2016-02-10 CN claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513332-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN disclosed
US-4276225-A PHOSPHOLINE OXIDE OR PHOSPHETANE OXIDE SOLVENT BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US disclosed