Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611856 | 0.87 | GUSB (0.45) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5611545 | 0.86 | GUSB (0.42) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5612074 | 0.84 | GUSB (0.41) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5612460 | 0.82 | GUSB (0.43) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL4750784 | 0.82 | DHFR (0.53) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5611677 | 0.80 | PDE5A (0.42) | GUSBMEN1LMNAGAAHPGD | |
| SCHEMBL1688987 | 0.79 | GUSB (0.43) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5611661 | 0.79 | TNKS (0.39) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5612557 | 0.78 | DHFR (0.41) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5611811 | 0.77 | DHFR (0.61) | GUSBPIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | disclosed |