SCHEMBL561207

SCHEMBL561207

O=C(O)C=CC(F)(F)C(F)(F)CF

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
GABRR1 P24046 2/20 0.32
GABRR2 P28476 2/20 0.32
BLM P54132 2/20 0.32
GABRR3 A8MPY1 1/20 0.32
LMNA P02545 1/20 0.32
APEX1 P27695 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755844 0.86 TSHR (0.33) TSHRTP53EGLN1EGLN3GABRR1
SCHEMBL5360468 0.85 TSHR (0.32) TSHRTP53EGLN1EGLN3
SCHEMBL4340454 0.83 TSHR (0.31) TSHRTP53EGLN1EGLN3
SCHEMBL5412517 0.83 TSHR (0.31) TSHRTP53EGLN1EGLN3
Bicarbonate SCHEMBL20598987 0.76
SCHEMBL29581456 0.75 TSHR (0.40) TSHRTP53EGLN1EGLN3GABRR1
SCHEMBL7148039 0.74 TSHR (0.31) TSHRTP53EGLN1EGLN3
SCHEMBL899316 0.74 TSHR (0.44) TSHRTP53EGLN1EGLN3GABRR1
SCHEMBL899318 0.74 TSHR (0.44) TSHRTP53EGLN1EGLN3GABRR1
SCHEMBL32684399 0.71 TBXAS1 (0.37) TSHRTP53EGLN1EGLN3GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060267-A Regenerated PET composite material and preparation method thereof 上海中镭新材料科技有限公司 2024-12-03 CN claimed
EP-4182737-B1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-07-03 EP claimed
EP-2563273-B1 INTRAVITREOUS SELF ADAPTIVE STENT EMPIRE TECHNOLOGY DEV LLC (US) 2017-08-23 EP claimed
US-9539087-B2 Intravitreous self adaptive stent EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-01-10 US claimed
EP-3074116-A1 FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING B.G. Negev Technologies and Applications Ltd. (IL) 2016-10-05 EP claimed
US-20160263530-A1 FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) 2016-09-15 US claimed
WO-2015079442-A1 FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) 2015-06-04 WO claimed
EP-2563273-A1 INTRAVITREOUS SELF ADAPTIVE STENT Empire Technology Development LLC (US) 2013-03-06 EP claimed
EP-2091985-B1 REVERSIBLE MICELLES AND APPLICATIONS FOR THEIR USE UNIV LEEDS (GB) 2013-02-20 EP claimed
US-20120035738-A1 INTRAVITREOUS SELF ADAPTIVE STENT CRESTLINE DIRECT FINANCE, L.P. 2012-02-09 US claimed
US-6653426-B2 Radially expandable; coaxial polymer comprising pentafluoropropyl acrylate and (heptadecyl fluorodecyl methacrylate) comonomers QUANAM MEDICAL CORPORATION 2003-11-25 US claimed
US-20030149470-A1 Polymer compositions for intraluminal stent QUANAM MEDICAL CORPORATION 2003-08-07 US claimed
US-6530950-B1 Radially expandable; rigid and flexible regions; polymer of such as pentafluoropropyl acrylate, polyethylene glycol methacrylate and methylmethacrylate QUANAM MEDICAL CORPORATION 2003-03-11 US claimed
EP-0835294-B1 LIGHT DIFFUSING ADHESIVE MINNESOTA MINING & MFG (US) 2003-01-29 EP claimed
EP-1140242-B1 POLYMER COMPOSITIONS FOR INTRALUMINAL STENT QUANAM MEDICAL CORP (US) 2002-10-30 EP claimed
EP-0981418-B1 INTRAOCULAR LENS TUMBLING PROCESS USING COATED BEADS BAUSCH & LOMB SURGICAL INC (US) 2002-06-26 EP claimed
EP-1140242-A1 POLYMER COMPOSITIONS FOR INTRALUMINAL STENT Quanam Medical Corporation (US) 2001-10-10 EP claimed
EP-0568652-B1 WAVEGUIDE SENSOR FIBERCHEM INC (US) 2000-10-11 EP claimed
WO-2000041738-A1 POLYMER COMPOSITIONS FOR INTRALUMINAL STENT QUANAM MEDICAL CORPORATION (US) 2000-07-20 WO claimed
EP-0036272-B1 PERMANENT DENTAL RESTORATIVE COMPOSITIONS AND METHODS OF USING THEM ROHM AND HAAS COMPANY (US) 1985-01-09 EP claimed