Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611734 | 0.85 | DHFR (0.55) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL5611470 | 0.85 | DHFR (0.55) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL5612000 | 0.82 | DHFR (0.52) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL5611669 | 0.82 | DHFR (0.51) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL5611495 | 0.81 | DHFR (0.50) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL1689135 | 0.80 | DHFR (0.49) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL5611826 | 0.80 | DHFR (0.49) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL1689302 | 0.80 | DHFR (0.49) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL4701748 | 0.80 | DHFR (0.38) | DHFRALDH1A1HPGDTSHRPTGS2 | |
| SCHEMBL5767436 | 0.80 | DHFR (0.58) | DHFRALDH1A1HPGDTSHRTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | disclosed |