Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701714 | 0.92 | GRM1 (0.40) | DHFRALDH1A1HPGDTSHRDHODH | |
| SCHEMBL4699473 | 0.88 | TDP2 (0.45) | DHFRALDH1A1HPGDTSHRDHODH | |
| SCHEMBL5612502 | 0.80 | DHFR (0.53) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL4165879 | 0.77 | RIPK2 (0.40) | RIPK2PSDPTGS2AOC3 | |
| SCHEMBL4163364 | 0.77 | GRM1 (0.41) | TSHRRIPK2PTGS2AOC3 | |
| SCHEMBL4169659 | 0.76 | GRM1 (0.58) | ALDH1A1HPGDTSHR | |
| SCHEMBL4704624 | 0.75 | TDP2 (0.48) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL4699312 | 0.75 | TDP2 (0.46) | DHFRALDH1A1HPGDTSHRTNKS | |
| SCHEMBL4703457 | 0.74 | GRM1 (0.40) | ALDH1A1RIPK2PTGS2AOC3 | |
| SCHEMBL5611826 | 0.73 | DHFR (0.49) | DHFRALDH1A1HPGDTSHRTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999132-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM, LLC (BM) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007120454-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2007-10-25 | — | — | WO | disclosed |