Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5613205 | 0.78 | DRD2 (0.43) | DRD2DRD1HTR2AHTR2CHTR2B | |
| SCHEMBL2079607 | 0.74 | HTR2C (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL5613174 | 0.74 | HCRTR1 (0.32) | DRD2DRD1 | |
| SCHEMBL5604265 | 0.68 | HTR2C (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL5612831 | 0.68 | HTR2C (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL21041640 | 0.67 | HTR2C (0.45) | HTR2C | |
| SCHEMBL5612854 | 0.66 | HTR2C (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL5593821 | 0.66 | HTR2A (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL22355459 | 0.65 | NTRK1 (0.35) | — | |
| SCHEMBL22355454 | 0.65 | NTRK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140213-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | WO | claimed |