Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399359 | 0.98 | RARB (0.49) | RARBHSD17B10TSHRALDH1A1ESR1 | |
| SCHEMBL21215485 | 0.95 | SKP2 (0.47) | RARBHSD17B10TSHRALDH1A1TP53 | |
| SCHEMBL27992110 | 0.90 | GPR3 (0.50) | RARBALDH1A1HTR2AGPR3 | |
| SCHEMBL4737345 | 0.89 | GPR3 (0.54) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL7466244 | 0.83 | HSD11B1 (0.50) | RARBHSD17B10TSHRALDH1A1ESR1 | |
| SCHEMBL9400273 | 0.82 | RAB9A (0.42) | RARBHSD17B10ALDH1A1ESR1ADRA2A | |
| SCHEMBL9398826 | 0.81 | RAB9A (0.50) | RARBHSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL18885486 | 0.80 | HSD17B10 (0.51) | RARBHSD17B10TSHRALDH1A1ESR1 | |
| SCHEMBL9398982 | 0.79 | RARB (0.68) | RARBHSD17B10TSHRALDH1A1ESR1 | |
| SCHEMBL9399850 | 0.79 | RARB (0.65) | RARBHSD17B10TSHRALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867624-A1 | Method for manufacturing 2-bromo-4,4'-dialkyl biphenyl | Saltigo GmbH (DE) | 2007-12-19 | — | — | EP | disclosed |