SCHEMBL5613530

SCHEMBL5613530

Oc1ccccc1-c1ccc2[nH]nnc2c1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALOX15 P16050 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 1/20 0.37
ALOX12 P18054 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
DCUN1D1 Q96GG9 1/20 0.33
F7 P08709 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83054 0.80 MGAM (0.43) IDO1ALOX15HPGDHSD17B10DCUN1D1
SCHEMBL29501455 0.80 MGAM (0.43) IDO1ALOX15HPGDHSD17B10DCUN1D1
SCHEMBL6064915 0.80 MEN1 (0.39) IDO1KMT2AMEN1ALOX15HPGD
SCHEMBL1628801 0.80 DPP4 (0.37) IDO1KMT2AMEN1ALOX15HPGD
SCHEMBL30117209 0.80 MEN1 (0.39) IDO1KMT2AMEN1ALOX15HPGD
SCHEMBL5612694 0.79 METAP2 (0.37) KMT2AMEN1HPGDHSD17B10SMN1; SMN2
SCHEMBL30640430 0.79 MGAM (0.42) IDO1ALOX15HPGDHSD17B10DCUN1D1
SCHEMBL9951530 0.78 CYP3A4 (0.37) IDO1MAPT
Hydrochloric Acid SCHEMBL28371375 0.78 METAP2 (0.36) KMT2AMEN1HPGDHSD17B10SMN1; SMN2
SCHEMBL8962327 0.75 MGAM (0.39) IDO1ALOX15HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070128442-A1 Materials composites of a moulded article of transparent or translucent dyeable plastics moulding compounds EMS-CHEMIE AG (CH) 2007-06-07 US disclosed
WO-2005075190-A1 MATERIALS COMPOSITES OF A MOULDED ARTICLE OF TRANSPARENT OR TRANSLUCENT DYEABLE PLASTICS MOULDING COMPOUNDS EMS-CHEMIE AG (CH) 2005-08-18 WO disclosed