SCHEMBL1628801

SCHEMBL1628801

Oc1ccccc1-c1ccc2[nH]nnc2c1Cc1c(-c2ccccc2O)ccc2[nH]nnc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.37
IDO1 P14902 5/20 0.37
MGAM O43451 2/20 0.33
GAA P10253 2/20 0.33
F7 P08709 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
DCUN1D1 Q96GG9 1/20 0.33
TTR P02766 1/20 0.33
ALDH1A1 P00352 3/20 0.32
GFER P55789 1/20 0.32
ALOX15 P16050 2/20 0.32
ADORA2A P29274 1/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
BCL2L1 Q07817 1/20 0.32
GUSB P08236 1/20 0.32
TP53 P04637 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5613530 0.80 IDO1 (0.38) IDO1MGAMGAAF7SI
SCHEMBL8218688 0.80 MGAM (0.33) IDO1MGAMGAAF7SI
SCHEMBL83054 0.79 MGAM (0.43) IDO1MGAMGAAF7SI
SCHEMBL29501455 0.79 MGAM (0.43) IDO1MGAMGAAF7SI
SCHEMBL991777 0.78 IDO1 (0.36) IDO1MGAMGAASIMGAM2
SCHEMBL30640430 0.78 MGAM (0.42) IDO1MGAMGAAF7SI
SCHEMBL10797942 0.74 GRIN2B (0.42) ALDH1A1ALOX15HSD17B10HPGDBCL2L1
SCHEMBL8962327 0.74 MGAM (0.39) IDO1MGAMGAAF7SI
SCHEMBL2726716 0.74 MGAM (0.39) IDO1MGAMGAAF7SI
SCHEMBL7099284 0.73 CYP3A4 (0.38) GAATP53MAPK1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2775993-B1 SOLID ANTI-SUN COMPOSITION BASED ON LIPOPHILIC ORGANIC UV SCREENING AGENT AND AEROGEL PARTICLES OF HYDROPHOBIC SILICA OREAL (FR) 2018-10-24 EP disclosed
US-9233056-B2 Solid anti-sun composition based on lipophilic organic UV screening agent and aerogel particles of hydrophobic silica L'OREAL (FR) 2016-01-12 US disclosed
US-9078820-B2 Oil-in-water emulsion containing an amphiphilic polymer and a silicone elastomer L'OREAL (FR) 2015-07-14 US disclosed
US-20140294975-A1 SOLID ANTI-SUN COMPOSITION BASED ON LIPOPHILIC ORGANIC UV SCREENING AGENT AND AEROGEL PARTICLES OF HYDROPHOBIC SILICA L'OREAL (FR) 2014-10-02 US disclosed
EP-2775993-A1 SOLID ANTI-SUN COMPOSITION BASED ON LIPOPHILIC ORGANIC UV SCREENING AGENT AND AEROGEL PARTICLES OF HYDROPHOBIC SILICA L'Oréal (FR) 2014-09-17 EP disclosed
WO-2013068236-A1 SOLID ANTI-SUN COMPOSITION BASED ON LIPOPHILIC ORGANIC UV SCREENING AGENT AND AEROGEL PARTICLES OF HYDROPHOBIC SILICA L'OREAL (FR) 2013-05-16 WO disclosed
US-20110088711-A1 WIPE WITH AN EMULSION CONTAINING A THICKENING POLYMER AND A HYDROPHOBIC MODIFIED INULIN L'OREAL (FR) 2011-04-21 US disclosed
US-20100221296-A1 OIL-IN-WATER EMULSION CONTAINING AN AMPHIPHILIC POLYMER AND A SILICONE ELASTOMER L'OREAL (FR) 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110088711-A1 WIPE WITH AN EMULSION CONTAINING A THICKENING POLYMER AND A HYDROPHOBIC MODIFIED INULIN WIZ, CUTA, WAPL DPP4 4614/4885IDO1 115/4885MGAM 323/4885
US-20100221296-A1 OIL-IN-WATER EMULSION CONTAINING AN AMPHIPHILIC POLYMER AND A SILICONE ELASTOMER IDUA, PLOD3, ABHD16A DPP4 4774/4885IDO1 3029/4885MGAM 334/4885
US-20140294975-A1 SOLID ANTI-SUN COMPOSITION BASED ON LIPOPHILIC ORGANIC UV SCREENING AGENT AND AEROGEL PARTICLES OF HYDROPHOBIC SILICA CUTA, DSG1, KRT18 DPP4 4547/4885IDO1 3618/4885MGAM 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.