Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009577 | 1.00 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17504462 | 0.86 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17504460 | 0.86 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28522703 | 0.84 | LMNA (0.58) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5385338 | 0.83 | KDM4E (0.59) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL5385330 | 0.83 | KDM4E (0.59) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL27841658 | 0.81 | NFE2L2 (0.56) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL285232 | 0.81 | ABCG2 (0.71) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL285231 | 0.81 | ABCG2 (0.71) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL30560976 | 0.81 | ABCG2 (0.71) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747059-A1 | PERVAPORATION COMPOSITE MEMBRANES | McMaster University (CA) | 2007-01-31 | — | — | EP | claimed |
| WO-2005102503-A1 | PERVAPORATION COMPOSITE MEMBRANES | MCMASTER UNIVERSITY (CA) | 2005-11-03 | — | — | WO | claimed |