Fomesafen

Fomesafen

SCHEMBL5613618

CC(N)=O.CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
TTR P02766 1/20 0.67
PPOX P50336 1/20 0.67
MRGPRX4 Q96LA9 1/20 0.46
FLT1 P17948 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
SCN9A Q15858 5/20 0.44
LMNA P02545 3/20 0.43
POLB P06746 2/20 0.43
MAPT P10636 1/20 0.43
CCR6 P51684 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
FFAR1 O14842 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PYGL P06737 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL39607 0.96 TDP1 (0.71) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL30120750 0.96 TDP1 (0.71) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL29366195 0.96 TDP1 (0.71) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL16881788 0.96 TDP1 (0.71) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL8539654 0.96 TDP1 (0.71) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL11022545 0.96 TDP1 (0.66) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL466794 0.95 TDP1 (0.70) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL467115 0.95 TDP1 (0.70) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL467001 0.95 TDP1 (0.70) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL17110535 0.95 TDP1 (0.69) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8551918-B2 Herbicidal composition SYNGENTA CROP PROTECTION LLC (US) 2013-10-08 US disclosed
US-20070197387-A1 Herbicidal Composition SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 US disclosed
EP-1689227-A2 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2006-08-16 EP disclosed
WO-2005055716-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197387-A1 Herbicidal Composition DDT, HDHD5, DERL1 TDP1 1427/4885MEN1 2770/4885KMT2A 1983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.