Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fomesafen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A known ✓ | Q15858 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | PPOX | P50336 | 1/20 | 0.70 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fomesafen SCHEMBL39607 | 0.99 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL30120750 | 0.99 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL29366195 | 0.99 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL16881788 | 0.99 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL8539654 | 0.99 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL467115 | 0.98 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL467001 | 0.98 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL17110535 | 0.97 | TDP1 (0.69) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL5613618 | 0.95 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL18765365 | 0.95 | TDP1 (0.66) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260101896-A1 | AQUEOUS HERBICIDAL CONCENTRATES | MONSANTO TECHNOLOGY LLC (US) | 2026-04-16 | — | — | US | claimed |
| US-12389906-B2 | Aqueous herbicidal concentrates | MONSANTO TECHNOLOGY LLC (US) | 2025-08-19 | — | — | US | claimed |
| CN-119400965-A | Sodium ion battery electrolyte and sodium ion battery prepared from same | 湖南钠方新能源科技有限责任公司 | 2025-02-07 | — | — | CN | claimed |
| US-20210386063-A1 | AQUEOUS HERBICIDAL CONCENTRATES | MONSANTO TECHNOLOGY LLC (US) | 2021-12-16 | — | — | US | claimed |
| EP-3107384-B1 | AQUEOUS HERBICIDAL CONCENTRATES | MONSANTO TECHNOLOGY LLC (US) | 2021-12-15 | — | — | EP | claimed |
| EP-3917319-A1 | MICROENCAPSULATED ACETAMIDE HERBICIDES | Monsanto Technology LLC (US) | 2021-12-08 | — | — | EP | claimed |
| US-11140900-B2 | Aqueous herbicidal concentrates | MONSANTO TECHNOLOGY LLC (US) | 2021-10-12 | — | — | US | claimed |
| WO-2020160223-A1 | MICROENCAPSULATED ACETAMIDE HERBICIDES | MONSANTO TECHNOLOGY LLC (US) | 2020-08-06 | — | — | WO | claimed |
| EP-3107384-A1 | AQUEOUS HERBICIDAL CONCENTRATES | Monsanto Technology LLC (US) | 2016-12-28 | — | — | EP | claimed |
| US-20150208653-A1 | AQUEOUS HERBICIDAL CONCENTRATES | MONSANTO TECHNOLOGY LLC (US) | 2015-07-30 | — | — | US | claimed |
| WO-2015113015-A1 | AQUEOUS HERBICIDAL CONCENTRATES | MONSANTO TECHNOLOGY LLC (US) | 2015-07-30 | — | — | WO | claimed |
| US-20260114444-A1 | PESTICIDAL COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260101896-A1 | AQUEOUS HERBICIDAL CONCENTRATES | MONSANTO TECHNOLOGY LLC (US) | 2026-04-16 | — | — | US | disclosed |
| US-20260096553-A1 | MICROENCAPSULATED HERBICIDES | MONSANTO TECHNOLOGY LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-12550892-B2 | Herbicidal compositions | MONSANTO TECHNOLOGY LLC (US) | 2026-02-17 | — | — | US | disclosed |
| EP-2403343-A1 | HERBICIDAL FORMULATIONS | Syngenta Limited (GB) | 2012-01-11 | — | — | EP | disclosed |
| EP-2403535-A1 | COMPATIBILIZED ELECTROLYTE FORMULATIONS | Syngenta Participations AG (CH) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010102102-A1 | COMPATIBILIZED ELECTROLYTE FORMULATIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100424-A1 | HERBICIDAL FORMULATIONS | SYNGENTA LIMITED (GB) | 2010-09-10 | — | — | WO | disclosed |
| US-6147030-A | SYNERGISTIC MIXTURE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260114444-A1 | PESTICIDAL COMPOSITIONS | NOTUM, WEE1, DDT | SCN9A 2796/4885TDP1 2555/4885MEN1 430/4885 |
| US-20260096553-A1 | MICROENCAPSULATED HERBICIDES | DDT, HPD, CYP3A43 | SCN9A 4603/4885TDP1 2073/4885MEN1 3010/4885 |
| US-20260101896-A1 | AQUEOUS HERBICIDAL CONCENTRATES | PPOX, UROD, HPD | SCN9A 3717/4885TDP1 1301/4885MEN1 2987/4885 |
| US-12550892-B2 | Herbicidal compositions | DDT, HDHD5, AQP3 | SCN9A 2526/4885TDP1 3795/4885MEN1 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.