Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5613463 | 0.80 | TAAR1 (0.32) | — | |
| SCHEMBL5613303 | 0.78 | DPP4 (0.33) | TSHRLMNADPP4F2 | |
| SCHEMBL20568160 | 0.72 | DPP4 (0.39) | TSHRLMNAMAPK1DPP4F2 | |
| SCHEMBL5596091 | 0.67 | LMNA (0.42) | TSHRLMNAMAPK1SLC6A4 | |
| SCHEMBL5596124 | 0.64 | LMNA (0.35) | LMNAMAPK1 | |
| SCHEMBL4774509 | 0.63 | DPP4 (0.45) | TSHRLMNAMAPK1DPP4F2 | |
| SCHEMBL5595943 | 0.61 | TRPA1 (0.35) | LMNA | |
| SCHEMBL1494253 | 0.61 | DPP4 (0.43) | TSHRLMNAMAPK1DPP4F2 | |
| SCHEMBL842216 | 0.61 | DPP4 (0.43) | TSHRLMNAMAPK1DPP4F2 | |
| SCHEMBL8386068 | 0.59 | DPP4 (0.41) | TSHRLMNAMAPK1DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |