Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595943 | 0.83 | TRPA1 (0.35) | LMNATRPA1HTR2ATAAR1KDM4E | |
| SCHEMBL5596219 | 0.80 | ALDH1A1 (0.37) | LMNATRPA1HTR2ATAAR1KDM4E | |
| SCHEMBL20568160 | 0.74 | DPP4 (0.39) | LMNAHTR2ATAAR1CYP2D6SRC | |
| SCHEMBL5596580 | 0.74 | TRPA1 (0.34) | LMNATRPA1HTR2ATAAR1KDM4E | |
| SCHEMBL5595935 | 0.71 | TRPA1 (0.33) | LMNATRPA1 | |
| SCHEMBL7935090 | 0.70 | LMNA (0.39) | LMNATRPA1HTR2ATAAR1KDM4E | |
| SCHEMBL5596091 | 0.68 | LMNA (0.42) | LMNAHTR2ATAAR1KDM4ECYP2D6 | |
| SCHEMBL5596479 | 0.67 | ALDH1A1 (0.35) | LMNAKDM4EL3MBTL1CYP2D6SRC | |
| SCHEMBL5613303 | 0.67 | DPP4 (0.33) | LMNAHTR2ATAAR1KDM4ECYP2D6 | |
| SCHEMBL3454935 | 0.67 | TRPA1 (0.38) | LMNATRPA1HTR2ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |