Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615471 | 0.70 | KDM4E (0.42) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL11144286 | 0.70 | CYP1A2 (0.40) | KDM4ETSHRMAPTCYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL1072120 | 0.69 | ALDH1A1 (0.43) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL28517555 | 0.68 | KDM4E (0.54) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL6131357 | 0.68 | ALDH1A1 (0.42) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL6131362 | 0.68 | LMNA (0.42) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL12533961 | 0.67 | TSHR (0.52) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL12533960 | 0.67 | TSHR (0.52) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL867710 | 0.67 | LMNA (0.52) | LMNAKDM4EMMP2TSHRMAPT | |
| SCHEMBL12533959 | 0.67 | TSHR (0.52) | LMNAKDM4EMMP2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007111499-A1 | PROCESS FOR THE PREPARATION OF A LINEAR POLYETHYLENE | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2007-10-04 | — | — | WO | disclosed |