Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1072120 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL6131362 | 0.82 | LMNA (0.42) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL6131340 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL28517555 | 0.74 | KDM4E (0.54) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL5615471 | 0.69 | KDM4E (0.42) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| Hydrochloric Acid SCHEMBL1074386 | 0.68 | LMNA (0.39) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL5615466 | 0.68 | LMNA (0.41) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL12533957 | 0.66 | TSHR (0.52) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL12533961 | 0.66 | TSHR (0.52) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL12533960 | 0.66 | TSHR (0.52) | ALDH1A1LMNAKDM4EMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919412-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| US-6911516-B1 | Copolymers of ethylene with c3-c12 α-olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-06-28 | — | — | US | disclosed |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | ALDH1A1 4462/4885LMNA 3742/4885KDM4E 3587/4885 |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | ALDH1A1 4462/4885LMNA 3742/4885KDM4E 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.