SCHEMBL5616144

SCHEMBL5616144

Cc1cc(C)c(N)c(-c2cccc3ccccc23)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.48
CYP1A2 P05177 4/20 0.48
DHFR P00374 1/20 0.44
ALDH1A1 P00352 5/20 0.44
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA9 Q16790 3/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
HPGD P15428 4/20 0.40
HSD17B10 Q99714 4/20 0.40
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
KEAP1 Q14145 1/20 0.39
PIM1 P11309 1/20 0.39
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29164460 0.82 CYP2A6 (0.56) CYP2A6CYP1A2DHFRALDH1A1CA12
SCHEMBL3962186 0.80 CTSD (0.41) CYP2A6CYP1A2DHFRALDH1A1HSD17B10
SCHEMBL7951078 0.80 CYP1A2 (0.57) CYP2A6CYP1A2DHFRALDH1A1CA12
SCHEMBL17500079 0.79 CYP1A2 (0.48) CYP2A6CYP1A2ALDH1A1CA12CA1
SCHEMBL21883719 0.79 DHFR (0.44) CYP2A6CYP1A2DHFRALDH1A1CA12
SCHEMBL30978224 0.79 CA12 (0.49) CYP2A6CYP1A2DHFRALDH1A1CA12
SCHEMBL22517355 0.79 CA12 (0.49) CYP2A6CYP1A2DHFRALDH1A1CA12
SCHEMBL20609436 0.78 CYP2A6 (0.55) CYP2A6CYP1A2DHFRALDH1A1CA12
SCHEMBL3789931 0.78 ALDH1A1 (0.52) CYP2A6CYP1A2ALDH1A1MAOBHSD17B10
SCHEMBL1011515 0.77 MAOB (0.50) CYP2A6CYP1A2DHFRALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007023618-A1 HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-01 WO disclosed