Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615786 | 0.76 | KDM4E (0.41) | ALDH1A1KMT2AMAPTLMNAKCNH2 | |
| SCHEMBL3954442 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2APOLBTDP1LMNA | |
| SCHEMBL5599046 | 0.73 | TDP1 (0.39) | ALDH1A1KMT2APOLBMAPTTDP1 | |
| SCHEMBL5616308 | 0.71 | L3MBTL1 (0.39) | ALDH1A1KMT2APOLBMAPTLMNA | |
| SCHEMBL5601214 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBMAPTLMNA | |
| SCHEMBL5615878 | 0.71 | L3MBTL1 (0.38) | ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL1466191 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBMAPTLMNA | |
| Butyl Chloride SCHEMBL27485209 | 0.68 | KDM4E (0.56) | ALDH1A1KMT2APOLBMAPTTDP1 | |
| SCHEMBL27721562 | 0.68 | KMT2A (0.56) | ALDH1A1KMT2APOLBMAPTTLR8 | |
| SCHEMBL4899071 | 0.68 | MAPT (0.54) | ALDH1A1KMT2APOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746986-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | claimed |
| WO-2005097099-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | claimed |