Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615786 | 0.85 | KDM4E (0.41) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5615878 | 0.82 | L3MBTL1 (0.38) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL4060494 | 0.74 | KDM4E (0.44) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5616306 | 0.71 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL5616114 | 0.68 | L3MBTL1 (0.41) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL19582677 | 0.67 | L3MBTL1 (0.40) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL28702194 | 0.67 | TLR8 (0.41) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL20372906 | 0.67 | TLR8 (0.41) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5599568 | 0.66 | KDM4E (0.50) | L3MBTL1KDM4EMAPTCYP2D6KMT2A | |
| SCHEMBL5600154 | 0.66 | ALDH1A1 (0.48) | ALDH1A1POLBKMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746986-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | claimed |
| WO-2005097099-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | claimed |