Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407836 | 0.89 | NR1H4 (0.45) | MAPTKMT2AALDH1A1KDM4EHTT | |
| SCHEMBL5593328 | 0.89 | RXFP1 (0.43) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL5592971 | 0.87 | RXFP1 (0.42) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4414236 | 0.87 | NAMPT (0.43) | ALDH1A1KDM4EHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL5592986 | 0.86 | RXFP1 (0.41) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4551631 | 0.86 | GRM4 (0.49) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4417707 | 0.85 | CYP3A4 (0.43) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4419761 | 0.83 | CYP1A2 (0.49) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4411700 | 0.82 | MEN1 (0.43) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4551944 | 0.80 | NR1H4 (0.46) | MAPTKMT2AMEN1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |