Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411700 | 0.89 | MEN1 (0.43) | NR1H4PPARGPPARARXFP1MEN1 | |
| SCHEMBL5593330 | 0.86 | RXFP1 (0.43) | NR1H4PPARGPPARARXFP1MEN1 | |
| SCHEMBL5593328 | 0.86 | RXFP1 (0.43) | NR1H4PPARGPPARARXFP1MEN1 | |
| SCHEMBL4413480 | 0.85 | RAF1 (0.45) | NR1H4RXFP1MEN1KMT2AMAPT | |
| SCHEMBL4412543 | 0.84 | ALDH1A1 (0.42) | NR1H4RXFP1MEN1KMT2AMAPT | |
| SCHEMBL4415213 | 0.83 | RAF1 (0.45) | RXFP1MEN1KMT2AMAPTRAF1 | |
| SCHEMBL4409369 | 0.83 | RAB9A (0.51) | MEN1KMT2ATSHRRAF1BRAF | |
| SCHEMBL4419761 | 0.83 | CYP1A2 (0.49) | MEN1KMT2AMAPTTSHRHTT | |
| SCHEMBL4407836 | 0.83 | NR1H4 (0.45) | NR1H4PPARGPPARARXFP1KMT2A | |
| SCHEMBL5592971 | 0.83 | RXFP1 (0.42) | NR1H4PPARGPPARARXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |