SCHEMBL5616459

SCHEMBL5616459

CC1=CC([Zr](Cl)Cl)c2cccc(Br)c21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.34
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2970600 0.76 PBRM1 (0.36) PBRM1ALDH1A1
SCHEMBL14008642 0.75 PBRM1 (0.34) PBRM1ALDH1A1
Hydrochloric Acid SCHEMBL5616456 0.73 PBRM1 (0.35) PBRM1ALDH1A1
SCHEMBL911070 0.72 GPR3 (0.33)
SCHEMBL2973832 0.70 GID4 (0.37) PBRM1ALDH1A1
SCHEMBL2960706 0.70 PBRM1 (0.46) PBRM1ALDH1A1
SCHEMBL2959658 0.69 PBRM1 (0.38) PBRM1ALDH1A1
SCHEMBL5000105 0.68 PBRM1 (0.32) PBRM1
SCHEMBL2959986 0.67 KDM1A (0.37) PBRM1ALDH1A1
SCHEMBL2975128 0.67 PBRM1 (0.34) PBRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833858-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Patents Inc. (US) 2007-09-19 EP claimed
WO-2006065906-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO claimed