Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616925 | 0.93 | TLR7 (0.48) | TLR7 | |
| SCHEMBL5617118 | 0.92 | FAAH (0.48) | TLR7 | |
| SCHEMBL4143705 | 0.91 | SMN1; SMN2 (0.44) | TOP2A | |
| SCHEMBL5617058 | 0.86 | TLR8 (0.44) | TLR7TOP2A | |
| SCHEMBL4158992 | 0.85 | TNF (0.48) | TLR7TOP2A | |
| SCHEMBL5617227 | 0.84 | TOP2A (0.46) | TOP2A | |
| SCHEMBL4147393 | 0.84 | FAAH (0.48) | TLR7TOP2A | |
| SCHEMBL5617063 | 0.83 | FAAH (0.48) | TLR7TOP2A | |
| SCHEMBL4138665 | 0.83 | FAAH (0.50) | TLR7TOP2A | |
| SCHEMBL4011233 | 0.83 | FAAH (0.50) | TLR7TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697873-B2 | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-15 | — | — | US | disclosed |
| US-20070219196-A1 | AMIDE SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219196-A1 | AMIDE SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES | IL2, IL4, IFNG | TLR7 123/4885TOP2A 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.