Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12075159 | 0.73 | MKNK1 (0.46) | MAPK8MAPK9MAPK10CYP11B1CYP11B2 | |
| SCHEMBL18797697 | 0.72 | MKNK1 (0.38) | MAPK8MAPK9MAPK10CYP11B1CYP11B2 | |
| SCHEMBL12075537 | 0.69 | IRAK4 (0.57) | MAPK8MAPK9MAPK10MKNK1MKNK2 | |
| SCHEMBL31020506 | 0.69 | IRAK4 (0.57) | MAPK8MAPK9MAPK10MKNK1MKNK2 | |
| SCHEMBL21801556 | 0.69 | LRRK2 (0.43) | MAPK8MAPK9MAPK10CYP11B1CYP11B2 | |
| SCHEMBL2189180 | 0.68 | HRH3 (0.44) | MAPK8MAPK9MAPK10CYP11B1CYP11B2 | |
| SCHEMBL13052911 | 0.67 | CYP11B2 (0.55) | CYP11B1CYP11B2LRRK2MGAMGAA | |
| SCHEMBL729956 | 0.67 | KDM4E (0.56) | CYP11B1CYP11B2LRRK2MGAMGAA | |
| SCHEMBL30270004 | 0.67 | KDM4E (0.56) | CYP11B1CYP11B2LRRK2MGAMGAA | |
| SCHEMBL22345403 | 0.67 | LRRK2 (0.44) | MAPK8MAPK9MAPK10CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | MAPK8 2667/4885MAPK9 1740/4885MAPK10 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.