Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811866 | 0.96 | HPRT1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL10484322 | 0.96 | HPRT1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL5618062 | 0.89 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL29913753 | 0.89 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL27456577 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL10484075 | 0.88 | HPRT1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL9798242 | 0.84 | CYP2A6 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL10348677 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL11622042 | 0.80 | AKR1B1 (0.49) | ALDH1A1HSD17B10HIF1ACYP1B1KIF11 | |
| SCHEMBL19186626 | 0.79 | KIF11 (0.59) | ALDH1A1HSD17B10KIF11CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110462040-A | Regulation of polypeptide expression by novel gene switch expression systems | INTREXON CORP | 2019-11-15 | — | — | CN | claimed |
| CN-110198949-A | It is used to prepare 9 β, the technique of 10 α-progesterone (inverse progesterone) | 工业化学有限公司 | 2019-09-03 | — | — | CN | claimed |
| CN-106714770-A | Hydroxysteroid compounds, intermediates thereof, preparation method, composition and uses thereof | 斯法尔制药私人有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-106536539-A | Chemical compounds and use thereof for improving muscular quality | 比奥菲蒂斯公司 | 2017-03-22 | — | — | CN | claimed |
| CN-106420767-A | 6-substituted estradiol derivatives for use in remyelination of nerve axons | 安德斯有限责任公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106255501-A | 6-substituted estradiol derivatives for the treatment of alzheimer's disease | 恩德切有限责任公司 | 2016-12-21 | — | — | CN | claimed |
| CN-106046100-A | 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives, methods for the production thereof and the use thereof for treating diseases | 拜耳知识产权有限责任公司 | 2016-10-26 | — | — | CN | claimed |
| CN-102471365-B | 17-hydroxy-17-pentafluorethyl female-4,9 (10)-diene 11-acetylenylbenzene radical derivative, its preparation method and the application in treatment illness thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-20 | — | — | CN | claimed |
| CN-102471366-B | 17-hydroxy-17-pentafluoroethylestra-4, 9(10) -diene 11-benzylidene derivatives, process for preparing them and their use for treating diseases | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-16 | — | — | CN | claimed |
| CN-105073119-A | Novel 11 beta-hydroxysteroid compounds for use in mitochondrial biogenesis and diseases associated with mitochondrial dysfunction or depletion | SPHAERA PHARMA PRIVATE LTD | 2015-11-18 | — | — | CN | claimed |
| CN-103501790-A | 6-substituted estradiol derivatives for remyelination of nerve axons | ENDECE LLC | 2014-01-08 | — | — | CN | claimed |
| CN-102471365-A | 17-hydroxy-17-pentafluoroethylestra-4, 9(10) -diene 11-ethynylphenyl derivatives, method for the production thereof and use thereof for treating diseases | BAYER SCHERING PHARMA AG | 2012-05-23 | — | — | CN | claimed |
| CN-105916845-B | N- heteroaryl compound and composition for inhibiting the active N- azaspiro cycloalkanes of SHP2 to replace | 诺华股份有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-110291097-A | Steroid compounds and protein-conjugates thereof | 里珍纳龙药品有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-110198949-A | It is used to prepare 9 β, the technique of 10 α-progesterone (inverse progesterone) | 工业化学有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-110099915-A | Glucocorticoid receptor inhibitors | 欧瑞克制药公司 | 2019-08-06 | — | — | CN | disclosed |
| US-4623661-A | HYDROXAMIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0199151-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0125701-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |
| US-4060677-A | Process for molecular weight lowering of vinyl halide polymers employing saturated carbon to carbon bonded aldehydes | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |